Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeru
Drug resistance and tolerance greatly diminish the therapeutic potential of antibiotics against pathogens. Antibiotic tolerance by...
Detection of pathogenic biofilms with bacterial amyloid targeting fluorescent probe, CDy11
Bacterial biofilms are responsible for a wide range of persistent infections. In the clinic, diagnosis of biofilm-associated infections...
In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology
Bacterial cells are able to form surface-attached biofilm communities known as biofilms by encasing themselves in extracellular polymeric...
RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Re
The alternative sigma factor RpoN regulates many cell functions, such as motility, quorum sensing, and virulence in the opportunistic...
PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysacchari
Biofilms are surface-associated communities of microorganism embedded in extracellular matrix. Exopolysaccharide is a critical component...
The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presenc
Pseudomonas aeruginosa is a clinically relevant species involved in biofilm-based chronic infections. We provide evidence that the P....
Biofilms of pathogenic nontuberculous mycobacteria targeted by new therapeutic approaches
Microbial infections of the cornea are potentially devastating and can result in permanent visual loss or require vision rescuing...
Chemical Biology Strategies for Biofilm Control
Microbes live as densely populated multicellular surface-attached biofilm communities embedded in self-generated, extracellular polymeric...
In silico analyses of metagenomes from human atherosclerotic plaque samples
Background Through several observational and mechanistic studies, microbial infection is known to promote cardiovascular disease. Direct...
Anditalea andensis ANESC-ST - An Alkaliphilic Halotolerant Bacterium Capable of Electricity Generati
A great challenge in wastewater bioremediation is the sustained activity of viable microorganisms, which can contribute to the breakdown...